Police, fire and ambulance crews are on the A350 at Pertwood, near Warminster, after a head-on accident just after 4pm today.
One man was trapped after the incident, involving a Ford Focus and a Renault Trafic Van.
The driver of the other vehicle suffered a fractured right arm and right leg in the incident, while the passenger had minor injuries.
Police have put a road closure in place at Longbridge Deverill and are asking road users to find an alternate route to avoid delays.
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